My 3rd party library RPATH problem (Linux)

[wysota]

Is there a way for replacing those linker absolute paths (e.g. /home/username/QtSDK/Simulator/QtMobility/gcc/lib/) with an empty ones?

Not really. What you can do is not add any rpath entries at all. Clearing QMAKE_LIBDIRS (or something like that) should do the trick.