yes.. you can create GUI using QT Creator/designer. Similar to your 'hello world' application you have to cross compile the Qt source.

First -> you have to create make file for cross compilation, by using qmake command in your cross compile tool chain.

qmake path\project_name.pro

Sencond -> then do make using 'make' command in your cross compile tool chain. similar to your hello world.

Note - instead of doing the above steps in command line, you can configure cross compiler in Qt Creator itself. refer below link under 'Configure Qt Creator' section

http://developer.toradex.com/how-to/...embedded-linux

Third -> Once the compilation completed, Copy the generated bin file to your target board & execute with -qws keyword.

./filename -qws

- qws is used to mention run time environment that, currently running application is QWS_Server


For more info refer link.... http://doc.qt.io/qt-4.8/qt-embedded-running.html